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THP (Standard)

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-13725R
    Pirarubicin (Standard)

    THP (Standard)

    		 Reference Standards Topoisomerase Autophagy Bacterial Antibiotic Infection Cancer
    Pirarubicin (Standard) is the analytical standard of Pirarubicin. This product is intended for research and analytical applications. Pirarubicin is an anthracycline antibiotics, acts as a topoisomerase II inhibitor, and is a widely used for treatment of various cancers, in particular, solid tumors.
    Pirarubicin (Standard)
  • HY-13725AR
    Pirarubicin Hydrochloride (Standard)

    THP Hydrochloride (Standard)

    		 Reference Standards Topoisomerase Autophagy Bacterial Antibiotic Infection Cancer
    Pirarubicin (Hydrochloride) (Standard) is the analytical standard of Pirarubicin (Hydrochloride). This product is intended for research and analytical applications. Pirarubicin Hydrochloride is an anthracycline antibiotics, acts as a topoisomerase II inhibitor, and is a widely used for treatment of various cancers, in particular, solid tumors.
    Pirarubicin Hydrochloride (Standard)
  • HY-14926R
    Levonadifloxacin (Standard)

    (S)-(-)-Nadifloxacin (Standard); WCK 771 (Standard)

    		 Reference Standards Antibiotic Bacterial Infection
    Levonadifloxacin (Standard) is the analytical standard of Levonadifloxacin. This product is intended for research and analytical applications. Levonadifloxacin ((S)-(-)-Nadifloxacin; WCK 771) is a broad-spectrum anti-staphylococcal agent. Levonadifloxacin shows antibacterial activity against Methicillin (HY-121544)-susceptible Staphylococcus aureus (MSSA) and Methicillin-resistant S. aureus (MRSA) strains, with a reduction of which phagocytized in THP-1 monocytes .
    Levonadifloxacin (Standard)
  • HY-119698R
    BAP9THP (Standard)

    SD 8339 (Standard); N-Benzyl-9-(tetrahydro-2h-pyran-2-yl)adenine (Standard)

    		 Drug Derivative Reference Standards Others
    BAP9THP (Standard) is the analytical standard of BAP9THP. This product is intended for research and analytical applications. BAP9THP is a synthetic cytokinin derivative and a growth regulator. BAP9THP promotes chlorophyll retention (and senescence delay) in plant tissues exceptionally strongly, and growth of tobacco callus almost as strongly as 6-Benzylaminopurine (BAP). BAP9THP induces adventitious shoot formation ignificantly more strongly than N6-isopentenyladenine or Kinetin .
    BAP9THP (Standard)
  • HY-104073R
    CAY10602 (Standard)

    		Reference Standards Sirtuin Metabolic Disease Inflammation/Immunology
    CAY10602 (Standard) is the analytical standard of CAY10602 (HY-104073). This product is intended for research and analytical applications. CAY10602 is a SIRT1 activator. CAY10602 dose-dependently suppresses the NF-κB-dependent induction of TNF-α by lipopolysaccharide in THP-1 cells .
    CAY10602 (Standard)
  • HY-108670R
    AZ 11645373 (Standard)

    		Reference Standards P2X Receptor Inflammation/Immunology
    AZ 11645373 (Standard) is the analytical standard of AZ 11645373 (HY-108670). This product is intended for research and analytical applications. AZ11645373 is a highly selective and potent antagonist at human but not rat P2X7 receptors，AZ11645373 inhibits ATP-evoked IL-1β release from lipopolysaccharide-activated THP-1 cells , with an IC50 value of 90 nM .
    AZ 11645373 (Standard)
  • HY-100688R
    ML390 (Standard)

    		Reference Standards Dihydroorotate Dehydrogenase Cancer
    ML390 (Standard) is the analytical standard of ML390 (HY-100688). This product is intended for research and analytical applications. ML390 is a potent dihydroorotate dehydrogenase (DHODH) inhibitor. ML390 is an inducer of myeloid differentiation and causes myeloid differentiation in murine (ER-HoxA9) and human (U937 and THP1) acute myeloid leukemia (AML) models .
    ML390 (Standard)
  • HY-100401AR
    Pactimibe sulfate (Standard)

    CS-505 (Standard)

    		 Acyltransferase Reference Standards Cardiovascular Disease
    Pactimibe (sulfate) (Standard) is the analytical standard of Pactimibe (sulfate) (HY-100401A). This product is intended for research and analytical applications. Pactimibe sulfate (CS-505) is a dual ACAT1/2 inhibitor with IC50s of 4.9 μM and 3.0 μM, respectively. Pactimibe sulfate (CS-505) inhibits ACAT with IC50s of 2.0 μM, 2.7 μM, 4.7 μM in the liver, macrophages and THP-1 cells, respectively . Pactimibe sulfate (CS-505) noncompetitively inhibits oleoyl-CoA with a Ki value of 5.6 μM. Moreover, Pactimibe sulfate (CS-505) obviously inhibits cholesteryl ester formation with an IC50 of 6.7 μM. Pactimibe sulfate (CS-505) possesses anti-atherosclerotic potential with lowering plasma cholesterol activity .
    Pactimibe sulfate (Standard)

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