1 Result for "

TIC10g

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "TIC10g" in MCE Product Catalog:

Cat. No.: HY-162649
CAS No.: 754998-88-4
TIC10g is a dual inhibitor for toll-like receptor 7 and 9 (TLR7 and TLR9), which inhibits TLR7 and TLR9 mediated TNF-α release in mouse macrophages (IC50 is 14.5 μM and 6.5 μM) and human B lymphocytes (IC50 is 7.69 μM and 11.5 μM). TIC10g inhibits the activation of NF-κB and MAPK, and exhibits anti-inflammatory activity against systemic lupus erythematosus and rheumatoid arthritis .
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