1 Result for "

TL4-12

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "TL4-12" in MCE Product Catalog:

Cat. No.: HY-123714
CAS No.: 1620820-12-3
Purity:  99.55%
Target:  

MAP4K Apoptosis

Research Areas:  

Inflammation/Immunology Cancer

TL4-12 is a selective MAP4K2/GCK inhibitor, dose-dependently downregulates IKZF1 and BCL-6 and leads to MM cell proliferation inhibition (IC50=37 nM) accompanied by induction of apoptosis. TL4-12 can be used to overcome immunomodulatory agent resistance in multiple myeloma (MM) .
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