1 Result for "

TLQP-62

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "TLQP-62" in MCE Product Catalog:

Cat. No.: HY-P11092
Target:  

Endogenous Metabolite

Research Areas:  

Neurological Disease

TLQP-62 (mouse,rat) is a secreted C-terminal peptide that can be derived from protein VGF. TLQP-62 activates the BDNF-TrkB signaling pathway, inducing acute, transient phosphorylation of TrkB receptor and downstream CREB (Ser133) phosphorylation. TLQP-62 demonstrates excellent efficacy in promoting long-term fear memory formationin wild-type mice and reversing memory impairment in VGF heterozygous knock-out mice. TLQP-62 can be used for the study of memory-related neurological disorders (e.g., Alzheimer’s disease, frontotemporal dementia) .
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