3 Results for "

TNP-470

" in MedChemExpress (MCE) Product Catalog:
Products (3)

3 Results for "TNP-470" in MCE Product Catalog:

2
2 Cited Publications
Cat. No.: HY-101932
CAS No.: 129298-91-5
Purity:  99.87%
Synonyms: AGM-1470
Target:  

Aminopeptidase

Research Areas:  

Cardiovascular Disease Cancer

TNP-470 is a methionine aminopeptidase-2 inhibitor and also an angiogenesis inhibitor.
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Cat. No.: HY-101932R
CAS No.: 129298-91-5
Synonyms: AGM-1470 (Standard)
TNP-470 (Standard) is the analytical standard of TNP-470 (HY-101932). This product is intended for research and analytical applications. TNP-470 is a methionine aminopeptidase-2 inhibitor and also an angiogenesis inhibitor.
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Cat. No.: HY-116861
CAS No.: 369358-07-6
Target:  

MetAP

Research Areas:  

Cancer

A-357300 is a reversible and selective MetAP2 inhibitor with IC50s of 0.12 and 57 μM against MetAP2 and MetAP1. A-357300 induces cytostasis by cell cycle arrest at the G1 phase selectively in endothelial cells and in a subset of tumor cells. A-357300 inhibits angiogenesis both in vitro and in vivo and shows potent antitumor efficacy in carcinoma, sarcoma, and neuroblastoma murine models. A-357300 can be used for the studies of neuroblastoma, fibrosarcoma and breast cancer .
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