1 Result for "

TRC210258

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "TRC210258" in MCE Product Catalog:

Cat. No.: HY-117912
CAS No.: 1431553-15-9
Target:  

Endogenous Metabolite

Research Areas:  

Cardiovascular Disease

TRC210258 is a TGR5 agonist with activity to improve diabetes-associated hyperglycemia and dyslipidemia. TRC210258 promotes energy expenditure by enhancing the release of glucagon-like peptide-1. TRC210258 is able to improve glucose metabolic control in high-fat diet-induced obese mice. TRC210258 also showed improvement in lipid parameters in high-fat-fed hamsters, including reductions in plasma triglyceride and low-density lipoprotein cholesterol levels. TRC210258 improved emerging lipid-related cardiovascular risk parameters including remnant cholesterol and triglyceride clearance .
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