1 Result for "

TS-41

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "TS-41" in MCE Product Catalog:

Cat. No.: HY-163006
CAS No.: 3020728-68-8
Target:  

EGFR c-Met/HGFR

Research Areas:  

Cancer

EGFR/c-Met-IN-1 (compound TS-41) is a dual-target inhibitor of EGFR/c-Met. The IC50 for inhibiting EGFR L858R and c-Met is 68.1 nM and 0.26 nM respectively. . EGFR/c-Met-IN-1 induces apoptosis and cell cycle arrest in A549-P cells, downregulating the phosphorylation of EGFR, c-Met, and downstream AKT. EGFR/c-Met-IN-1 inhibits tumor growth in vitro and in vivo .
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