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EGFR/c-Met-IN-1

EGFR/c-Met-IN-1 (compound TS-41) is a dual-target inhibitor of EGFR/c-Met. The IC50 for inhibiting EGFRL858R and c-Met is 68.1 nM and 0.26 nM respectively. . EGFR/c-Met-IN-1 induces apoptosis and cell cycle arrest in A549-P cells, downregulating the phosphorylation of EGFR, c-Met, and downstream AKT. EGFR/c-Met-IN-1 inhibits tumor growth in vitro and in vivo.

For research use only. We do not sell to patients.

  • CAS No.: 3020728-68-8
  • Formula: C30H25FN6O5
  • Molecular Weight:568.56
  • Storage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • EGFR/c-Met-IN-1 Chemical Structure
    EGFR/c-Met-IN-1 Chemical Structure
CAS No.: 3020728-68-8
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All EGFR Isoforms

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  • EGFR/c-Met-IN-1 Chemical Structure
    EGFR/c-Met-IN-1 Chemical Structure
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  • EGFR/c-Met-IN-1