1 Result for "

Thr200

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "Thr200" in MCE Product Catalog:

Cat. No.: HY-187174
Target:  

Carbonic Anhydrase

Research Areas:  

Cancer

CA IX-IN-6 is a selective human carbonic anhydrase IX (hCA IX) inhibitor, with Ki values of 8.9, 50.7, 551, and 64.4 nM against hCA IX, hCA XII, hCA I, and hCA II, respectively. CA IX-IN-6 binds to the active site via a classic sulfamide mode, coordinates with the catalytic Zn 2+ ion, forms a hydrogen bond with Thr200, and interacts with key active site residues. CA IX-IN-6 can be used in studies related to tumor-associated carbonic anhydrase inhibition .
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