3 Results for "

Tiotidine

" in MedChemExpress (MCE) Product Catalog:
Products (3)

3 Results for "Tiotidine" in MCE Product Catalog:

2
2 Cited Publications
Cat. No.: HY-101232
CAS No.: 69014-14-8
Purity:  98.53%
Synonyms: ICI 125211
Target:  

Histamine Receptor

Research Areas:  

Cardiovascular Disease

Tiotidine (ICI 125211) is a potent and selective antagonist of histamine H2-receptor (pA2=7.3-7.8 for guinea-pig right atrium). Tiotidine has low affinity for both the H1 and the H3 receptors .
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Cat. No.: HY-101232R
CAS No.: 69014-14-8
Synonyms: ICI 125211 (Standard)
Tiotidine (Standard) is the analytical standard of Tiotidine. This product is intended for research and analytical applications. Tiotidine (ICI 125211) is a potent and selective antagonist of histamine H2-receptor (pA2=7.3-7.8 for guinea-pig right atrium). Tiotidine has low affinity for both the H1 and the H3 receptors .
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Cat. No.: HY-136818
CAS No.: 95833-19-5
Target:  

Histamine Receptor

Research Areas:  

Endocrinology

DA 4643 (hydrochloride) is an H2 receptor antagonist with the chemical name 2-guanidino-4 (3-methylaminomethyleneiminophenyl) thiazole dihydrochloride. It has a weak interaction with cytochrome P-450 and has a less inhibitory effect on P-450 than cimetidine and tiotidine. DA 4643 (hydrochloride) is able to inhibit both enzymatic and non-enzymatic lipid peroxidation reactions. This inhibition may not be achieved by inhibiting agent metabolizing enzymes, but rather due to the antioxidant properties of the compound itself. Compared with other H2 receptor antagonists such as cimetidine, ranitidine and tiotidine, DA 4643 (hydrochloride) shows a unique effect in lipid peroxidation inhibition. These properties make DA 4643 (hydrochloride) a potential H2 receptor antagonist with multiple mechanisms of action.
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