8 Results for "

Type II diabete

" in MedChemExpress (MCE) Product Catalog:
Products (8)

8 Results for "Type II diabete" in MCE Product Catalog:

26
26 Publications Verification
Cat. No.: HY-112764
CAS No.: 160743-62-4
Purity:  98.40%
mPEG2000-DMG is used for the preparation of liposome for siRNA delivery with improved transfection efficiency in vitro. mPEG2000-DMG is also used for the lipid nanoparticle for an oral plasmid DNA delivery approach in vivo through a facile surface modification to improve the mucus permeability and delivery efficiency of the nanoparticles .
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3
3 Cited Publications
Cat. No.: HY-B2099A
CAS No.: 1190-53-0
Synonyms: 1-Butylbiguanide hydrochloride
Target:  

AMPK

Research Areas:  

Cancer

Buformin hydrochloride (1-Butylbiguanide hydrochloride), a potent AMPK activator, acts as an orally active biguanide antidiabetic agent. Buformin hydrochloride decreases hepatic gluconeogenesis and lowers blood glucose production in vivo. Buformin hydrochloride also has anti-cancer activities and is applied in cancer study (such as, cervical cancer and breast cancer, et al) .
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Cat. No.: HY-P10269
CAS No.: 2668298-70-0
Synonyms: GZR18
Target:  

GLP Receptor

Research Areas:  

Metabolic Disease

Bofanglutide (GZR18) is an analog of glucagon-like peptide-1 (GLP-1), which exhibits agonistic activity for GLP-1 receptor, with an EC50 of 0.677 nM. GZR18 ameliorates type 2 diabetes .
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Cat. No.: HY-148190
CAS No.: 1152810-23-5
Purity:  98.29%
Synonyms: CGT-8012
Target:  

Dipeptidyl Peptidase

Research Areas:  

Endocrinology

Sheng Gelieting (CGT-8012) is a dipeptidy peptidase-IV enzyme (DP-IV) inhibitor. Sheng Gelieting has great DP-IV inhibition activity with an IC50 value of 87 nM. Sheng Gelieting can be used for curing or preventing diseases relevant to the dipeptidy peptidase-IV enzyme, such as the diabetes, particularly the II-type diabete .
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Cat. No.: HY-B2099
CAS No.: 692-13-7
Synonyms: 1-Butylbiguanide
Target:  

AMPK

Research Areas:  

Metabolic Disease Cancer

Buformin (1-Butylbiguanide), a potent AMPK activator, acts as an orally active biguanide antidiabetic agent. Buformin decreases hepatic gluconeogenesis and lowers blood glucose production in vivo. Buformin also has anti-cancer activities and is applied in cancer study (such as, cervical cancer and breast cancer, et al) .
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Cat. No.: HY-19859
CAS No.: 1163719-08-1
Target:  

Dipeptidyl Peptidase

Research Areas:  

Metabolic Disease

AMG-222 (tosylate) is a DPP-IV inhibitor that can be used in the research of type II diabete .
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Cat. No.: HY-B2099AR
CAS No.: 1190-53-0
Synonyms: 1-Butylbiguanide hydrochloride (Standard)
Research Areas:  

Cancer

Buformin (hydrochloride) (Standard) is the analytical standard of Buformin (hydrochloride). This product is intended for research and analytical applications. Buformin hydrochloride (1-Butylbiguanide hydrochloride), a potent AMPK activator, acts as an orally active biguanide antidiabetic agent. Buformin hydrochloride decreases hepatic gluconeogenesis and lowers blood glucose production in vivo. Buformin hydrochloride also has anti-cancer activities and is applied in cancer study (such as, cervical cancer and breast cancer, et al) .
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Cat. No.: HY-W387035
CAS No.: 2799-15-7
Target:  

MHC

D-α-Methyl DOPA is an inhibitor of the binding of DQ8 peptide to MHC class II molecules. D-α-Methyl DOPA occupies a pocket along the DQ8 peptide binding groove. D-α-Methyl DOPA inhibits the binding of a DQ8 peptide to an MHC class II molecule for presentation to CD4 + T cells, thereby slowing the development or progression of type 1 diabete or celiac disease .
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