3 Results for "

U 72107-d4

" in MedChemExpress (MCE) Product Catalog:
Products (3)

3 Results for "U 72107-d4" in MCE Product Catalog:

Cat. No.: HY-13956S1
CAS No.: 1134163-31-7
Purity:  98.55%
Pioglitazone-d4 (alkyl) (U 72107-d4 (alkyl)) is the deuterium labeled Pioglitazone. Pioglitazone (U 72107) is a potent and selective PPARγ agonist with high affinity binding to the PPARγ ligand-binding domain with EC50 of 0.93 and 0.99 μM for human and mouse PPARγ, respectively .
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Cat. No.: HY-P72107
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: BRCC3; Lys-63-Specific Deubiquitinase BRCC36; Prev. CXorf53; BRCA1-A Complex Subunit BRCC36; BRCC36; BRISC Complex Subunit BRCC36; C6.1A; BRCA1/BRCA2-Containing Complex, Subunit 3; BRCA1/BRCA2-Containing Complex Subunit 36; Chromosome X Open Reading Frame
Species:  
Source:  
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Cat. No.: HY-E72107
Target:  

UGT

Research Areas:  

Others

Human UGT1A4 is a UDP-glucuronosyltransferase. Human UGT1A4 is the major enzyme catalyzing the glucuronidation of 25-hydroxyvitamin D3 (HY-32351) in the liver, and maintains vitamin D homeostasis by clearing 25-hydroxyvitamin D3. Human UGT1A4 regulates the substrate-dependent enzymatic activities of UGT1A1 and UGT1A6, while its own activity is also subject to substrate-dependent regulation by co-expressed UGT1A1 and UGT1A6 .
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