1 Result for "

UMK 57

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "UMK 57" in MCE Product Catalog:

Cat. No.: HY-122236
CAS No.: 342595-74-8
Purity:  99.52%
Research Areas:  

Cancer

UMK57 is a MCAK activator and kinetochore-microtubule destabilizer. UMK57 enhances MCAK-dependent microtubule depolymerization, increases kinetochore-microtubule turnover, reduces chromosome mis-segregation and lagging chromosomes, and inhibits cancer cell proliferation. UMK57 triggers adaptive resistance in Aurora B cancer cells via reversible Aurora B signaling pathway alterations. UMK57 can be used for the research of solid tumors .
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