1 Result for "

USP16-UBD

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "USP16-UBD" in MCE Product Catalog:

Cat. No.: HY-172193
Synonyms: SGC-UBD1031
Target:  

Deubiquitinase HDAC

Research Areas:  

Inflammation/Immunology Cancer

UBD1031 (SGC-UBD1031) is a selective USP16/HDAC6-UBD antagonist with a human USP16-UBD IC50 of 10.6 μM, KD value of 48 nM, and a human HDAC6-UBD KD of 16 nM. UBD1031 disrupts ISG15 C-terminus interactions with USP16-UBD and HDAC6-UBD, and exhibits cooperative inhibition of full-length USP16 deubiquitinase activity via USP16-UBD binding. UBD1031 can be used in research on cancer, autoimmune diseases, and Down syndrome .
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