1 Result for "

VAL-242

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "VAL-242" in MCE Product Catalog:

Cat. No.: HY-182062
CAS No.: 931366-46-0
Target:  

NAMPT E1/E2/E3 Enzyme

Research Areas:  

Neurological Disease

NAMPT activator-9 (Compound DIPM) is an allosteric, non-competitive NAMPT activator, with an EC50 of 3.366 μM against hNAMPT. NAMPT activator-9 enhances the enzymatic activity of NAMPT via an allosteric, non-competitive mechanism. NAMPT activator-9 increases intracellular NAD + levels. NAMPT activator-9 restores myotube diameter and reduces the expression of atrophy markers Atrogin-1 and MuRF1. NAMPT activator-9 is applicable to research related to muscle atrophy .
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