1 Result for "

VSP77

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "VSP77" in MCE Product Catalog:

Cat. No.: HY-133559
CAS No.: 1854008-12-0
Target:  

PPAR

Research Areas:  

Metabolic Disease

VSP-77 is an orally active PPARγ agonist. VSP-77 selectively upregulates the expression of insulin sensitivity-related genes (Glut4 and Adiponectin) by inhibiting CDK5-mediated phosphorylation of PPARγ at Ser-273. VSP-77 significantly improves glucose tolerance, reduces fasting blood glucose and insulin levels in high-fat diet (HFD)-induced diabetic mouse models. VSP-77 can be used for the study of diabetes .
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