1 Result for "

VVD442

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "VVD442" in MCE Product Catalog:

Cat. No.: HY-176811
CAS No.: 3055318-88-9
Target:  

Ras PI3K Akt

Research Areas:  

Cancer

VVD-442 is an inhibitor targeting PI3Kα. VVD-442 covalently binds to Cys242 in the RAS-binding domain of PI3K p110α, induces conformational changes, and disrupts the interaction between PI3K p110α and RAS proteins. VVD-442 also blocks RAS-mediated PI3K activation. VVD-442 can be used in research related to RAS-mutant cancers and HER2-overexpressing cancers .
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