1 Result for "

VX2 cells

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "VX2 cells" in MCE Product Catalog:

Cat. No.: HY-122224
CAS No.: 1590379-85-3
Target:  

Sigma Receptor

Research Areas:  

Cancer

SW43 is a Sigma-2 selective ligand and agonist. SW43 is an ideal molecule for the development of cancer-targeted drug compounds. SW43 conjugated with DOX-L-NETA ( 89Y) exhibits antitumor activity in a VX2 cancer liver tumor allograft rabbit model. SW 43 conjugated with SW IV-52s to form SW III-123 activates the NF-κB pathway, has potent cytotoxicity against ovarian cancer cell lines, and induces apoptosis .
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