5 Results for "

Vasoconstriction Inhibition

" in MedChemExpress (MCE) Product Catalog:
Products (5)

5 Results for "Vasoconstriction Inhibition" in MCE Product Catalog:

Cat. No.: HY-109163
CAS No.: 1706528-83-7
Purity:  99.62%
Synonyms: INS-1009
Treprostinil palmitil is a long-acting inhaled pulmonary vasodilator prodrug of Treprostinil (HY-100441), formulated in a lipid nanoparticle (LNP). Treprostinil palmitil can inhibit pulmonary vascular remodeling induced by Su/Hx challenge in rats. Treprostinil palmitil can induce cough. Treprostinil palmitil demonstrates a sustained presence in the lungs with reduced systemic exposure and prolonged inhibition of hypoxia-induced pulmonary vasoconstriction in vivo. Treprostinil palmitil can be studied in research for pulmonary arterial hypertension and interstitial lung disease .
loading...
    loading...
Cat. No.: HY-113654
CAS No.: 1026876-55-0
Target:  

TRP Channel

Research Areas:  

Others

AMG 7905 is a hypothermia-inducing transient receptor potential vanilloid type 1 (TRPV1) antagonist. AMG 7905 potentiates TRPV1 channels activation by protons and drives the reflectory inhibition of thermogenesis and tail-skin vasoconstriction, while potently blocking channel activation by capsaicin .
loading...
    loading...
Cat. No.: HY-113654A
Target:  

TRP Channel

Research Areas:  

Cardiovascular Disease

AMG 7905 TFA is a hypothermia-inducing transient receptor potential vanilloid type 1 (TRPV1) antagonist. AMG 7905 TFA potentiates TRPV1 channels activation by protons and drives the reflectory inhibition of thermogenesis and tail-skin vasoconstriction, while potently blocking channel activation by capsaicin .
loading...
    loading...
Cat. No.: HY-106123
CAS No.: 144702-17-0
Target:  

Angiotensin Receptor

Research Areas:  

Cardiovascular Disease

Pomisartan is an orally active angiotensin II receptor type AT1 antagonist (IC50=0.26 μM). Pomisartan works by inhibiting the binding of angiotensin II to the AT1 receptor, thereby blocking the vasoconstriction and aldosterone release caused by this interaction. Pomisartan results in a blood pressure-lowering effect .
loading...
    loading...
Cat. No.: HY-109163R
CAS No.: 1706528-83-7
Synonyms: INS-1009 (Standard)
Treprostinil palmitil (Standard) is the analytical standard of Treprostinil palmitil (HY-109163). This product is intended for research and analytical applications. Treprostinil palmitil is a long-acting inhaled pulmonary vasodilator prodrug of Treprostinil (HY-100441), formulated in a lipid nanoparticle (LNP). Treprostinil palmitil can inhibit pulmonary vascular remodeling induced by Su/Hx challenge in rats. Treprostinil palmitil can induce cough. Treprostinil palmitil demonstrates a sustained presence in the lungs with reduced systemic exposure and prolonged inhibition of hypoxia-induced pulmonary vasoconstriction in vivo. Treprostinil palmitil can be studied in research for pulmonary arterial hypertension and interstitial lung disease .
loading...
    loading...