1 Result for "

WGU55

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "WGU55" in MCE Product Catalog:

Cat. No.: HY-180217
Target:  

TMPRSS6 Factor Xa

Research Areas:  

Cardiovascular Disease

WGU55 is a selective and potent reversible type II transmembrane serine protease TMPRSS6 inhibitor with a Ki of 12.15 nM. WGU55 inhibits TMPRSS6 activity with an IC50 of 138 nMin KEK293 cells. WGU55 has a Ki of 3510 nM (SI = 289) against the homologous protease matriptase and a Ki of 5.2 μM against the coagulation key protease Factor Xa. WGU55 can be used for the research of iron overload related diseases, such as hereditary hemochromatosis .
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