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WM-derived hBMECs

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "WM-derived hBMECs" in MCE Product Catalog:

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β-Estradiol 17-acetate
β-Estradiol 17-acetate
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Cat. No.: HY-B0708
CAS No.: 1743-60-8
Synonyms: 1,3,5(10)-Estratriene-3,17β-diol 17-acetate
Category:  

Monophenols Animals Phenols Disease Research Fields Endocrinology Steroids

Target:  

Estrogen Receptor/ERR

β-Estradiol 17-acetate (1,3,5(10)-Estratriene-3,17β-diol 17-acetate) is a long-acting endogenous estrogen precursor and also a cell viability and proliferation enhancer. β-Estradiol 17-acetate promotes the adhesion and proliferation of freshly isolated and revived female-derived human brain microvascular endothelial cells, and reverses the decreased viability of revived male-derived human brain microvascular endothelial cells. β-Estradiol 17-acetate exerts the microvascular protective effect of estrogen, enabling non-tumor human brain microvascular endothelial cells to be cultured in vitro for 2 months after cryopreservation. β-Estradiol 17-acetate is biotransformed into β-estradiol via hydrolase action in the in vitro skin of humans, hairless dogs, rats and hairless mice .
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