1 Result for "

YK-2168

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "YK-2168" in MCE Product Catalog:

Cat. No.: HY-162919
CAS No.: 2571068-74-9
Target:  

CDK Apoptosis c-Myc

Research Areas:  

Cancer

YK-2168 is a potent and selective CDK9 inhibitor with an IC50 of 5.9 nM. YK-2168 inhibits phosphorylation of the CDK9 substrate pS2-RNA Pol II C-terminal domain. YK-2168 induces apoptosis in tumor cells, suppresses expression of CDK9-regulated genes including MYC and Mcl1, and inhibits tumor growth in CDX mice models. YK-2168 can be used for the research of cancer, such as leukemia .
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