1 Result for "

YM 114

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "YM 114" in MCE Product Catalog:

Cat. No.: HY-106909A
CAS No.: 153608-99-2
Synonyms: KAE-393
Target:  

5-HT Receptor

Research Areas:  

Cardiovascular Disease

YM114 (KAE-393) is a highly potent and selective (5-HT)3-receptor antagonist that does not affect Veratridine (HY-N6691)- or electrical stimulation-induced bradycardia in anesthetized rats. YM114 inhibits 2-methyl-5-HT (HY-19358)-induced Bezold-Jarisch reflex, which originates from (5-HT)3-receptor located on the endings of vagal afferent nerves in the heart .
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