1 Result for "

ZL55 cells

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "ZL55 cells" in MCE Product Catalog:

Cat. No.: HY-181590
Target:  

PROTACs SNIPERs YAP IAP

Research Areas:  

Cancer

PROTAC TEAD1/IAP degrader-3 is a TEAD1/IAP PROTAC degrader. PROTAC TEAD1/IAP degrader-3 recruits the cIAP1 and XIAP E3 ligases to form a ternary complex, drives proteasomal degradation of TEAD1, and triggers autoubiquitination and proteasomal degradation of cIAP1. PROTAC TEAD1/IAP degrader-3 inhibits cell proliferation. PROTAC TEAD1/IAP degrader-3 regulates Hippo pathway activity by downregulating CTGF gene expression in a TEAD-dependent manner. PROTAC TEAD1/IAP degrader-3 is applicable to the research of mesothelioma .
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