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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
4 Results for "
ZS3-046
" in MedChemExpress (MCE) Product Catalog:
Products (4)
4 Results for "ZS3-046" in MCE Product Catalog:
Cat. No.: HY-176457
CAS No.: 3087879-97-5
ZS3-046 is a potent TAF1 PROTAC degrader with a DC50 < 10 nM. ZS3-046 recruits the CRBN E3 ubiquitin ligase, promotes polyubiquitination and proteasomal degradation of TAF1, thereby activating p53 and downregulating c-Myc, and ultimately induces apoptosis of tumor cells. ZS3-046 can be used in research related to acute myeloid leukemia .
Cat. No.: HY-176467
CAS No.: 1926986-25-5
Research Areas:
TAF1 ligand 1 is a TAF1 ligand. TAF1 ligand 1 can be used as a Ligands for Target Protein for PROTAC synthesis, such as ZS3-046 (HY-176457) .
Cat. No.: HY-176470
Research Areas:
Thalidomide-N-C-piperidine-C7-Br, an E3 ligase ligand-linker conjugate, incorporates a cereblon (CRBN) ligand for the E3 ubiquitin ligase and a linker. Thalidomide-N-C-piperidine-C7-Br can be used in the synthesis of ZS3-046 (HY-176457) .
Cat. No.: HY-176469
Target:
Research Areas:
(1-(7-Bromoheptyl)piperidin-4-yl)methanamine is a PROTAC linker. (1-(7-Bromoheptyl)piperidin-4-yl)methanamine can be used in synthesis ZS3-046 (HY-176457) .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
