4 Results for "

alpha-toxin

" in MedChemExpress (MCE) Product Catalog:
Products (4)

4 Results for "alpha-toxin" in MCE Product Catalog:

Cat. No.: HY-P99583
CAS No.: 1629620-18-3
Synonyms: MEDI4893

Target:  

Bacterial

Research Areas:  

Infection Inflammation/Immunology

Suvratoxumab (MEDI4893) is a long-acting, high-affinity human anti-α-toxin monoclonal antibody (IgG1κ type). Suvratoxumab potently neutralizes α-toxin, a key S. aureus virulence factor. Suvratoxumab improves survival and reduces lung injury in an immunocompromised mice model of pneumonia. Suvratoxumab also enhances the antibacterial activity of Vancomycin (HY-B0671) or Linezolid (HY-10394) .
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Cat. No.: HY-P99551
CAS No.: 1374419-41-6
Synonyms: KBSA301; AR-301

Target:  

Antibiotic Bacterial

Research Areas:  

Infection

Tosatoxumab (AR-301; KBSA301) is a human immunoglobulin G1 monoclonal antibody that specifically neutralizes alpha-toxin (alpha-hemolysin; Hla) of S. aureus. Tosatoxumab binds to an N-terminal epitope of alpha-toxin, thereby preventing functional toxin pore oligomerisation. Tosatoxumab has the potential for passive immunotherapy in the S. aureus pneumonia as an adjunctive therapy to standard antibiotic agent. Recommend Isotope Control: Human IgG1 lambda1, Isotype Control (HY-P99992) .
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Cat. No.: HY-P1443
Target:  

Sodium Channel

Research Areas:  

Cancer

OD1 is a scorpion α-toxin that can be isolated from the venom of the Iranian yellow scorpion (Odonthobuthus doriae. OD1 is a modulator of mammalian Nav1.7 (EC50: 4.5 nM) .
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Cat. No.: HY-P99447
CAS No.: 1939108-95-8
Synonyms: ASN-1

Target:  

Bacterial

Research Areas:  

Infection

Atidortoxumab is a human IgG1κ monoclonal antibody that targets Staph aureus alpha toxin .
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