anionic phospholipid membranes

Pathways Recommended:	Membrane Transporter/Ion Channel

By Targets:	Antibiotic (1) Bacterial (2) Biochemical Assay Reagents (1) Endogenous Metabolite (1) Fungal (1) Liposome (6) PKC (1)
By Research Areas:	Cancer (1) Infection (3)
Oligonucleotides:	Phospholipids (5)

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-141571

DOPG sodium 3 Publications Verification Dioleoylphosphatidylglycerol sodium	Liposome	Others
DOPG sodium is a naturally occurring anionic phospholipid, containing oleic acid (18:1) inserted at the sn-1 and sn-2 positions. DOPG can form a lipid bilayer in an aqueous solution and is used in the generation of micelles, liposomes, and other artificial membranes. DOPG also exhibits anti-inflammatory properties .

HY-P0270

Magainin 2 Magainin II	Bacterial Antibiotic Fungal	Infection
Magainin 2 (Magainin II) is an antimicrobial peptide (AMP) isolated from the skin of the African clawed frog Xenopus laevis. Magainin 2 displays antibiotic activity against numerous gram-negative and gram-positive bacteria. Magainin 2 also is active against protozoa . Magainin 2 exerts its cytotoxicity effects by preferential interactions with anionic phospholipids abundant in bacterial membranes .

HY-W440986

Distearoylphosphatidylserine sodium DSPS sodium	Liposome	Others
Distearoylphosphatidylserine sodium is an anionic phospholipid with stearic acid tails (18:0) and contains a carboxylic acid (COOH) and amine (NH2) in their head group. It has been used in the preparation of lipid-mixing vesicles, liposome, or artificial membrane. Due to the medium size of fatty acid chain, DLPS is used to form thinner membranes/walls.

HY-W714524

1-Palmitoyl-2-oleoyl-sn-glycero-3-PS sodium 16:0-18:1 PS (POPS)	Liposome	Others
2-Oleoyl-1-palmitoyl-sn-glycero-3-phospho-L-serine sodium (16:0-18:1 PS (POPS)) is an anionic phospholipid with oleic acid (18:1) and palmitic acid (16:0) tails containing a carboxylic acid (COOH) and amine (NH2) in their head group. 2-Oleoyl-1-palmitoyl-sn-glycero-3-phospho-L-serine sodium has been used in the preparation of lipid-mixing vesicles, liposomes, and artificial membranes .

HY-142991

1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphatidylglycerol POPG	Liposome	Others
1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphatidylglycerol (POPG) is an anionic phosphatidylglycerol that often serves as a key component to co-construct model phospholipid bilayers with phosphatidylcholine (e.g., at a 3:1 POPC:POPG ratio) for investigating the structure and dynamics of transmembrane proteins. 1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphatidylglycerol acts as a fundamental material for mimicking the physicochemical properties of biological membranes and enables the elucidation of membrane protein interaction mechanisms .

HY-P11430

UBI (31-38)	Biochemical Assay Reagents	Infection
UBI (31-38) is a Ubiquicidin-derived octapeptide and anti-bacterial agent. UBI (31-38) selectively interacts with anionic phospholipid membranes and restricts lipid lateral motion. UBI (31-38) induces anionic vesicle aggregation via electrostatic repulsion screening, and undergoes conformational changes in membrane-mimicking environments. UBI (31-38) can be used for the research of infection imaging probes .

HY-W440985

DLPS 1,2-dilauroyl-sn-glycero-3-phospho-L-serine	Liposome	Cancer
DLPS is an anionic phospholipid with lauric acid tails (12:0) and contains a carboxylic acid (COOH) and amine (NH2) in their head group. It has been used in the preparation of lipid-mixing vesicles, liposome, or artificial membrane. Due to the medium size of fatty acid chain, DLPS is used to form thinner membranes/walls.

HY-W838254

1,2-Dipentadecanoyl-sn-glycero-3-phospho-(1'-rac-glycerol) sodium	PKC Endogenous Metabolite	Others
1,2-Dipentadecanoyl-sn-glycero-3-phospho-(1'-rac-glycerol) sodium functions as an activator for the protein kinase C family and is an anionic phospholipid found in mitochondrial and microsomal membranes, playing a crucial role in the composition of lung surfactant, particularly within the membranes of lamellar bodies in the lungs.

HY-P10455

Cys-Pexiganan TFA	Bacterial	Infection
Cys-Pexiganan TFA is an amphiphilic antimicrobial peptide. Cys-Pexiganan TFA exhibits antibacterial activities against Staphylococcus aureus and Pseudomonas aeruginosa, with MIC of 16 μg/mL and 64.0 μg/mL. Cys-Pexiganan TFA interacts with anionic phospholipids and DNA of microbial cell membranes, disintegrates the cells and leads to cell death .

HY-W714524A

1-Palmitoyl-2-oleoyl-sn-glycero-3-PS 16:0-18:1 PS (POPS) free acid	Liposome	Others
2-Oleoyl-1-palmitoyl-sn-glycero-3-phospho-L-serine (16:0-18:1 PS (POPS) free acid) is an anionic phospholipid with oleic acid (18:1) and palmitic acid (16:0) tails containing a carboxylic acid (COOH) and amine (NH2) in their head group. 2-Oleoyl-1-palmitoyl-sn-glycero-3-phospho-L-serine has been used in the preparation of lipid-mixing vesicles, liposomes, and artificial membranes .

Cat. No.	Product Name	Type

HY-141571

DOPG sodium 3 Publications Verification Dioleoylphosphatidylglycerol sodium	Biochemical Assay Reagents
DOPG sodium is a naturally occurring anionic phospholipid, containing oleic acid (18:1) inserted at the sn-1 and sn-2 positions. DOPG can form a lipid bilayer in an aqueous solution and is used in the generation of micelles, liposomes, and other artificial membranes. DOPG also exhibits anti-inflammatory properties .

HY-142991

1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphatidylglycerol POPG	Biochemical Assay Reagents
1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphatidylglycerol (POPG) is an anionic phosphatidylglycerol that often serves as a key component to co-construct model phospholipid bilayers with phosphatidylcholine (e.g., at a 3:1 POPC:POPG ratio) for investigating the structure and dynamics of transmembrane proteins. 1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphatidylglycerol acts as a fundamental material for mimicking the physicochemical properties of biological membranes and enables the elucidation of membrane protein interaction mechanisms .

1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphatidylglycerol

POPG

Biochemical Assay Reagents

1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphatidylglycerol (POPG) is an anionic phosphatidylglycerol that often serves as a key component to co-construct model phospholipid bilayers with phosphatidylcholine (e.g., at a 3:1 POPC:POPG ratio) for investigating the structure and dynamics of transmembrane proteins. 1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphatidylglycerol acts as a fundamental material for mimicking the physicochemical properties of biological membranes and enables the elucidation of membrane protein interaction mechanisms .

Cat. No.	Product Name	Target	Research Area

HY-P0270

Magainin 2 Magainin II	Bacterial Antibiotic Fungal	Infection
Magainin 2 (Magainin II) is an antimicrobial peptide (AMP) isolated from the skin of the African clawed frog Xenopus laevis. Magainin 2 displays antibiotic activity against numerous gram-negative and gram-positive bacteria. Magainin 2 also is active against protozoa . Magainin 2 exerts its cytotoxicity effects by preferential interactions with anionic phospholipids abundant in bacterial membranes .

HY-P11430

UBI (31-38)	Biochemical Assay Reagents	Infection
UBI (31-38) is a Ubiquicidin-derived octapeptide and anti-bacterial agent. UBI (31-38) selectively interacts with anionic phospholipid membranes and restricts lipid lateral motion. UBI (31-38) induces anionic vesicle aggregation via electrostatic repulsion screening, and undergoes conformational changes in membrane-mimicking environments. UBI (31-38) can be used for the research of infection imaging probes .

HY-P10455

Cys-Pexiganan TFA	Bacterial	Infection
Cys-Pexiganan TFA is an amphiphilic antimicrobial peptide. Cys-Pexiganan TFA exhibits antibacterial activities against Staphylococcus aureus and Pseudomonas aeruginosa, with MIC of 16 μg/mL and 64.0 μg/mL. Cys-Pexiganan TFA interacts with anionic phospholipids and DNA of microbial cell membranes, disintegrates the cells and leads to cell death .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-P0270

Magainin 2 Magainin II	Infection Structural Classification Natural Products Animals Classification of Application Fields Disease Research Fields Source Classification	Bacterial Antibiotic Fungal
Magainin 2 (Magainin II) is an antimicrobial peptide (AMP) isolated from the skin of the African clawed frog Xenopus laevis. Magainin 2 displays antibiotic activity against numerous gram-negative and gram-positive bacteria. Magainin 2 also is active against protozoa . Magainin 2 exerts its cytotoxicity effects by preferential interactions with anionic phospholipids abundant in bacterial membranes .

Cat. No.	Product Name		Classification

HY-141571

DOPG sodium 3 Publications Verification Dioleoylphosphatidylglycerol sodium		Phospholipids
DOPG sodium is a naturally occurring anionic phospholipid, containing oleic acid (18:1) inserted at the sn-1 and sn-2 positions. DOPG can form a lipid bilayer in an aqueous solution and is used in the generation of micelles, liposomes, and other artificial membranes. DOPG also exhibits anti-inflammatory properties .

HY-W440986

Distearoylphosphatidylserine sodium DSPS sodium		Phospholipids
Distearoylphosphatidylserine sodium is an anionic phospholipid with stearic acid tails (18:0) and contains a carboxylic acid (COOH) and amine (NH2) in their head group. It has been used in the preparation of lipid-mixing vesicles, liposome, or artificial membrane. Due to the medium size of fatty acid chain, DLPS is used to form thinner membranes/walls.

HY-W714524

1-Palmitoyl-2-oleoyl-sn-glycero-3-PS sodium 16:0-18:1 PS (POPS)		Phospholipids
2-Oleoyl-1-palmitoyl-sn-glycero-3-phospho-L-serine sodium (16:0-18:1 PS (POPS)) is an anionic phospholipid with oleic acid (18:1) and palmitic acid (16:0) tails containing a carboxylic acid (COOH) and amine (NH2) in their head group. 2-Oleoyl-1-palmitoyl-sn-glycero-3-phospho-L-serine sodium has been used in the preparation of lipid-mixing vesicles, liposomes, and artificial membranes .

HY-142991

1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphatidylglycerol POPG		Phospholipids
1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphatidylglycerol (POPG) is an anionic phosphatidylglycerol that often serves as a key component to co-construct model phospholipid bilayers with phosphatidylcholine (e.g., at a 3:1 POPC:POPG ratio) for investigating the structure and dynamics of transmembrane proteins. 1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphatidylglycerol acts as a fundamental material for mimicking the physicochemical properties of biological membranes and enables the elucidation of membrane protein interaction mechanisms .

HY-W440985

DLPS 1,2-dilauroyl-sn-glycero-3-phospho-L-serine		Phospholipids
DLPS is an anionic phospholipid with lauric acid tails (12:0) and contains a carboxylic acid (COOH) and amine (NH2) in their head group. It has been used in the preparation of lipid-mixing vesicles, liposome, or artificial membrane. Due to the medium size of fatty acid chain, DLPS is used to form thinner membranes/walls.

MCE Japan Authorized Agent ナミキ商事株式会社コスモ・バイオ株式会社重松貿易株式会社
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anionic phospholipid membranes

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