1 Result for "

auto-MARylation

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "auto-MARylation" in MCE Product Catalog:

Cat. No.: HY-125217
CAS No.: 2286261-72-9
Target:  

PARP

Research Areas:  

Cancer

PARP10-IN-1 is a PARP10 inhibitor with an IC50 of 1.8 μM, 2.7 μM, and >10-fold selectivity over most PARP family members, excluding PARP7 and PARP16.PARP10-IN-1 inhibits PARP10-mediated mono-ADP-ribosylation, including auto-MARylation of PARP10 and MARylation of its protein targets.PARP10-IN-1 is membrane permeable and inhibits PARP10-dependent MARylation in human embryonic kidney cells.PARP10-IN-1 can be used for the research of cancer .
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