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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
5 Results for "
autoinducer AI-2
" in MedChemExpress (MCE) Product Catalog:
Products (5)
5 Results for "autoinducer AI-2" in MCE Product Catalog:
Art. -Nr.: HY-W012927
CAS. Nr.: 19322-27-1
Synonyms: Chicory furaneol
Target:
Forschungsgebiete:
4-Hydroxy-5-methylfuran-3 (2H)-one (Chicory furaneol) is a mimic of bacterial quorum-sensing autoinducer AI-2. 4-Hydroxy-5-methylfuran-3 (2H)-one is produced by the yeast Saccharomyces cerevisiae, can be recognized by the AI-2 receptor LuxP of Vibrio harveyi and activate the AI-2-associated quorum-sensing signaling pathway, and is used for studying cross-species chemical communication and quorum-sensing mechanisms .
Art. -Nr.: HY-E71703
Target:
Forschungsgebiete:
3-Hydroxy-5-phosphonooxypentane-2,4-dione thiolase (EC 2.3.1.245) participates in a degradation pathway of the bacterial quorum-sensing autoinducer molecule AI-2.
Art. -Nr.: HY-E71072
Target:
Forschungsgebiete:
(4S)-4-Hydroxy-5-phosphonooxypentane-2,3-dione isomerase (EC 5.3.1.32) participates in a degradation pathway of the bacterial quorum-sensing autoinducer molecule AI-2.
Art. -Nr.: HY-182942
CAS. Nr.: 3112321-20-4
PV-DPD-19 is an autoinducer-2 (AI-2) quorum sensing inhibitor. PV-DPD-19 reduces AI-2 production and inhibits the expression of multiple MSCRAMMs. In co-culture systems with Staphylococcus aureus, PV-DPD-19 decreases the production of pyocyanin and Elastase in Pseudomonas aeruginosa. PV-DPD-19 impairs the adhesion ability of Staphylococcus aureus to lung epithelial cells. PV-DPD-19 inhibits biofilm formation of Pseudomonas aeruginosa (MBIC50 = 27 μg/mL) and Staphylococcus aureus (MBIC50 = 35 μg/mL). PV-DPD-19 shows no cytotoxicity in both in vitro lung epithelial cell models and in vivo Galleria mellonella larva models .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
