1 Result for "

cPKC

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "cPKC" in MCE Product Catalog:

Cat. No.: HY-129980A
CAS No.: 136449-85-9
Research Areas:  

Neurological Disease Cancer

NPC-15437 is a selective PKC inhibitor with an IC50 of 19 µM. NPC-15437 competitively inhibits phorbol ester- (Ki of 5 µM) and phosphatidylserine-induced (Ki of 12 µM) PKC activity. NPC-15437 does not inhibits cAMP-dependent or calcium/calmodulin-dependent protein kinases. NPC-15437 augments TRAIL-induced cell death in non-small cell lung cancer and medulloblastoma cells. NPC-15437 can be used for the research of non-small cell lung cancer, medulloblastoma, and neurological disease .
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