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cispla

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By Targets:	Autophagy (1) DNA Alkylator/Crosslinker (2) Drug Derivative (1) Ferroptosis (1) Fluorescent Dye (1) Liposome (1) Lipoxygenase (1) Pyroptosis (1) Src (1)
By Research Areas:	Cancer (4)
Oligonucleotides:	Liposome (1)

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Fluorescent Dye

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-17394

Cisplatin 765+ Cited Publications cis-Platinum; CDDP; cis-Diaminodichloroplatinum	DNA Alkylator/Crosslinker Ferroptosis Autophagy Pyroptosis Lipoxygenase	Cancer
Cisplatin (CDDP) is an antineoplastic chemotherapy agent by cross-linking with DNA and causing DNA damage in cancer cells. Cisplatin activates ferroptosis and induces autophagy .

HY-D2452

Cy3-Cisplatin 1 Publications Verification	Fluorescent Dye	Others
Cy3-Cisplatin is a Cyanine 3 fluorescent dye CY3 (HY-D0822) labled Cisplatin (HY-17394). Cy3-Cisplatin can be used for drug delivery, fluorescent labeling, cell imaging and tracking .

HY-161687

Cisplatin/Dasatinib prodrug-1	Src	Cancer
Cisplatin/Dasatinib prodrug-1 (Compound 3) is a prodrug of Cisplatin (HY-17394) and Dasatinib (HY-10181). Cisplatin/Dasatinib prodrug-1 exhibits antiproliferative activity against A2780, MDA-MB-231, MCF7, HCT116, RD, Thp1 and HL60 cancer cells with IC₅₀s of 0.1, 0.1, 0.36, 2.0, 0.4, 0.3 and 0.25 μM, respectively .

HY-154978

Cisplatin-resistant cells-IN-1	Drug Derivative	Cancer
Cisplatin-resistant cells-IN-1 (Compound 8) has high cytotoxicity against Cisplatin (HY-17394)-resistant cells. Cisplatin-resistant cells-IN-1 reduces the metabolic activity effectively in the low nanomolar range (IC₅₀: 0.14-1.79 μM in A549/A549-R, K562/K562-R, and MCF-7/MCF-7TamR cells) .

HY-185389

Cisplatin liposome Liposomal cisplatin	Liposome DNA Alkylator/Crosslinker	Cancer
Cisplatin liposome is a liposome-encapsulated form of Cisplatin (HY-17394). Cisplatin (CDDP) is an anti-tumor chemotherapeutic agent that cross-links with DNA, causing DNA damage in cancer cells. Cisplatin liposome prolongs drug circulation time and slowly releases the drug, allowing it to accumulate in the tumor and exert its killing effect.

Cat. No.	Product Name	Type

HY-D2452

Cy3-Cisplatin 1 Publications Verification	Fluorescent Dye
Cy3-Cisplatin is a Cyanine 3 fluorescent dye CY3 (HY-D0822) labled Cisplatin (HY-17394). Cy3-Cisplatin can be used for drug delivery, fluorescent labeling, cell imaging and tracking .

Cat. No.	Product Name		Classification

HY-185389

Cisplatin liposome Liposomal cisplatin		Liposome
Cisplatin liposome is a liposome-encapsulated form of Cisplatin (HY-17394). Cisplatin (CDDP) is an anti-tumor chemotherapeutic agent that cross-links with DNA, causing DNA damage in cancer cells. Cisplatin liposome prolongs drug circulation time and slowly releases the drug, allowing it to accumulate in the tumor and exert its killing effect.

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BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.

BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

MedchemExpress Validation 03

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred

MedchemExpress Validation 04

MedchemExpress Validation

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