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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
3 Results for "
cysteine cluster
" in MedChemExpress (MCE) Product Catalog:
Products (3)
3 Results for "cysteine cluster" in MCE Product Catalog:
Cat. No.: HY-170983
MC-25B is a DCAF16-recruiting FKBP12 PROTAC degrader with a DC50 of 0.35 μM. MC-25B promotes the formation of a ternary complex with DCAF16 and nuclear-localized FKBP12_NLS, thereby mediating DCAF16-dependent degradation of FKBP12_NLS via the proteasome and Cullin-RING ligase pathway .
Cat. No.: HY-E71575
Target:
Research Areas:
2-Iminoacetate synthase (EC 4.1.99.19) binds a [4Fe-4S] cluster that is coordinated by 3 cysteines and an exchangeable S-adenosyl-L-methionine molecule.
Cat. No.: HY-E71453U
Target:
Research Areas:
23S rRNA (uracil1939-C5)-Methyltransferase (EC 2.1.1.190) specifically methylates uracil1939 at C5 in 23S rRNA. 23S rRNA (uracil1939-C5)-Methyltransferase (EC 2.1.1.190) contains an [4Fe-4S] cluster coordinated by four conserved cysteine residues.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
