4 Results for "

dactolisib

" in MedChemExpress (MCE) Product Catalog:
Products (4)

4 Results for "dactolisib" in MCE Product Catalog:

69
Dactolisib
Dactolisib
0 Images
69 Publications Verification
Cat. No.: HY-50673
CAS No.: 915019-65-7
Synonyms: BEZ235; NVP-BEZ235
Target:  

PI3K mTOR Autophagy

Research Areas:  

Cancer

Dactolisib (BEZ235) is an orally active and dual pan-class I PI3K and mTOR kinase inhibitor with IC50s of 4 nM/5 nM/7 nM/75 nM, and 20.7 nM for p110α/p110γ/p110δ/p110β and mTOR, respectively. Dactolisib (BEZ235) inhibits both mTORC1 and mTORC2.
69
Dactolisib Tosylate
Dactolisib Tosylate
0 Images
69 Publications Verification
Cat. No.: HY-15174
CAS No.: 1028385-32-1
Purity:  99.87%
Synonyms: BEZ235 Tosylate; NVP-BEZ 235 Tosylate
Target:  

PI3K mTOR Autophagy

Research Areas:  

Cancer

Dactolisib Tosylate (BEZ235 Tosylate) is a dual PI3K and mTOR kinase inhibitor with IC50 values of 4, 75, 7, 5 nM for PI3Kα, β, γ, δ, respectively. Dactolisib Tosylate (BEZ235 Tosylate) inhibits mTORC1 and mTORC2.
65
Dactolisib hydrochloride
Dactolisib hydrochloride
0 Images
65 Cited Publications
Cat. No.: HY-50673A
CAS No.: 2319647-83-9
Synonyms: BEZ235 hydrochloride; NVP-BEZ235 hydrochloride
Target:  

PI3K mTOR Autophagy

Research Areas:  

Cancer

Dactolisib (BEZ235) hydrochloride is an orally active, dual pan-class I PI3K and mTOR inhibitor for p110α/γ/δ/β and mTOR with IC50 of 4 nM/5 nM/7 nM/75 nM and 20.7 nM, respectively. Dactolisib hydrochloride (BEZ235) inhibits mTORC1 and mTORC2 .
Dactolisib Tosylate (Standard)
Dactolisib Tosylate (Standard)
0 Images
Cat. No.: HY-15174R
CAS No.: 1028385-32-1
Synonyms: BEZ235 Tosylate (Standard); NVP-BEZ 235 Tosylate (Standard)
Target:  

PI3K mTOR Autophagy Reference Standards

Research Areas:  

Cancer

Dactolisib (Tosylate) (Standard) is the analytical standard of Dactolisib (Tosylate). This product is intended for research and analytical applications. Dactolisib Tosylate (BEZ235 Tosylate) is a dual PI3K and mTOR kinase inhibitor with IC50 values of 4, 75, 7, 5 nM for PI3Kα, β, γ, δ, respectively. Dactolisib Tosylate (BEZ235 Tosylate) inhibits mTORC1 and mTORC2.
Assay Types