2319647-83-9
2319647-83-9
Chemical Structure
Dactolisib hydrochloride
Synonym(s): BEZ235 hydrochloride; NVP-BEZ235 hydrochloride
- CAS No.: 2319647-83-9
- Formula:C30H24ClN5O
- Molecular Weight:506.00
InChIKey: VDZVGMJFBACERH-UHFFFAOYSA-N
SMILES: CN(C1=O)C2=C(C3=CC(C4=CC5=C(N=C4)C=CC=C5)=CC=C3N=C2)N1C6=CC=C(C=C6)C(C)(C#N)C.Cl
Biological Activity: Dactolisib (BEZ235) hydrochloride is an orally active, dual pan-class I PI3K and mTOR inhibitor for p110α/γ/δ/β and mTOR with IC50 of 4 nM/5 nM/7 nM/75 nM and 20.7 nM, respectively. Dactolisib hydrochloride (BEZ235) inhibits mTORC1 and mTORC2[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Dactolisib hydrochloride | 99.41% | Dactolisib (BEZ235) hydrochloride is an orally active, dual pan-class I PI3K and mTOR inhibitor for p110α/γ/δ/β and mTOR with IC50 of 4 nM/5 nM/7 nM/75 nM and 20.7 nM, respectively. Dactolisib hydrochloride (BEZ235) inhibits mTORC1 and mTORC2. | ||||||||||||||||||||
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References
Keywords
