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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
15 Results for "
double helical DNA
" in MedChemExpress (MCE) Product Catalog:
Products (15)
15 Results for "double helical DNA" in MCE Product Catalog:
1
1 Cited Publications
Research Areas:
Semustine is an orally active, blood-brain barrier permeable antitumor alkylating agent with a binding affinity of 1.53 × 10 3 M -1 for guanine and thymine residues in bovine DNA. Semustine undergoes major groove-directed alkylation at guanine residues to form O6-chloroethylguanine and N1-O6-ethanoguanine adducts, and generates dG-dC interstrand crosslinks. Semustine induces partial B- to C-type transition of DNA, base stacking and helical structure distortion, mild dehydration, as well as partial DNA double-strand unwinding. Semustine can be used in research related to Lewis lung cancer, leukemia, Hodgkin's lymphoma, malignant melanoma, glioma, and diffuse large B-cell lymphoma .
Cat. No.: HY-D1322
CAS No.: 2375105-86-3
Cat. No.: HY-D1095
CAS No.: 1268616-88-1
Cat. No.: HY-D1326
CAS No.: 1361402-15-4
Cat. No.: HY-D1097
CAS No.: 146397-17-3
Cat. No.: HY-D1316
CAS No.: 1557149-65-1
Cat. No.: HY-D1337
CAS No.: 1628790-40-8
Cat. No.: HY-D0968A
CAS No.: 1311966-47-8
Synonyms: Cyanine3 potassium
Cat. No.: HY-D1047
CAS No.: 68006-80-4
Cat. No.: HY-D1339
CAS No.: 2183440-63-1
Cat. No.: HY-D1414
Cat. No.: HY-D1415
Cat. No.: HY-DY1115
Target:
Research Areas:
Cyanine 3.18 (TEA) (solution) is a cyanine dye and fluorescent label for biomolecules. Cyanine 3.18 (TEA) (solution) interacts with double helical DNA via intercalation, minor groove binding, or DNA-templated aggregation .
Cat. No.: HY-DY2032
Target:
Research Areas:
Methyl Green Staining Solution (Chloroform-Extracted, 1%) is a basic dye stock solution with differential nucleic acid binding activity that distinguishes double-stranded DNA from RNA, and it can be used for assays related to nucleic acid distribution and DNA localization. Methyl Green Staining Solution (Chloroform-Extracted, 1%) functions by competitively binding to the phosphate groups of nucleic acids and stably binds to intact double-stranded DNA; RNA within the oocyte-specific ribonucleoprotein complex specifically binds to this dye, and RNase completely blocks this binding reaction. The nucleic acid recognition of Methyl Green Staining Solution (Chloroform-Extracted, 1%) depends on the size of the dye cation and the intact double-helical structure of DNA .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
