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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
8 Results for "
dwarfism
" in MedChemExpress (MCE) Product Catalog:
Products (8)
8 Results for "dwarfism" in MCE Product Catalog:
2
2 Cited Publications
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Research Areas:
Brassinazole is a selective triazole-type brassinosteroid (BR) biosynthesis inhibitor. Brassinazole is used for regulating plant growth and development .
Cat. No.: HY-P3503
CAS No.: 1480724-61-5
Synonyms: BMN 111
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Brassinazole (0.5, 1, 5 μM) causes markedly deformed seedlings, whose morphology is similar to that of BR-deficient mutants. Brassinazole causes cress dwarfism, altering leaf morphology such as the typical downward curl and dark green appearance of Arabidopsis BR-deficient mutants. However, administration of 10 nM BR reversed dwarfism .
Cat. No.: HY-115707
CAS No.: 126281-90-1
Synonyms: 16:0/0:0/18:3-DG; DG(16:0/0:0/18:3); 1-Palmitin-3-Linolenin
1-Palmitoyl-3-Linolenoyl-rac-glycerol (16:0/0:0/18:3-DG) is a diacylglycerol containing palmitic acid (HY-N0830) and α-linolenic acid (HY-N0728) at the sn-1 and sn-3 positions, respectively. It has been found in the peel and pulp of unripe Dwarf Cavendish bananas.
Cat. No.: HY-176547
CAS No.: 3069945-78-1
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FGFR2/3-IN-3 is a dual-target FGFR2/3 inhibitor with IC50s of 2.7 nM (TEL-FGFR2) and 3.9 nM (TEL-FGFR3), respectively. FGFR2/3-IN-3 has effective activity against both wild-type and mutant FGFR3. FGFR2/3-IN-3 has low CYP3A4 inhibitory effect and hERG toxicity. FGFR2/3-IN-3 improves the imbalance between chondrocyte proliferation and differentiation and promotes bone growth by inhibiting the signaling pathway mediated by mutant FGFR3. FGFR2/3-IN-3 shows a growth-promoting effect in a dwarfism mouse model and has the potential to study bone development disorder-related diseases such as achondroplasia (ACH) .
Cat. No.: HY-122833
CAS No.: 2833703-74-3
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FGFR3-IN-10 is a selective FGFR3 inhibitor that inhibits FGFR3 kinase activity. FGFR3-IN-10 can be used in research related to cancer, systemic sclerosis, fibrosis, pulmonary fibrosis, achondroplasia, lethal dwarfism, severe achondroplasia with developmental delay and acanthosis nigricans (SADDAN), and Muenke syndrome .
Cat. No.: HY-P72196
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: ACH; CD 333; CD333; CD333 antigen; CEK 2; CEK2; FGFR 3; FGFR-3; FGFR3; FGFR3_HUMAN; Fibroblast growth factor receptor 3 achondroplasia thanatophoric dwarfism; ; Fibroblast growth factor receptor 3; Heparin binding growth factor receptor; HSFGFR3EX; Hydroxyaryl protein kinase; JTK 4; JTK4; MFR 3; SAM 3; Tyrosine kinase JTK 4; Tyrosine kinase JTK4; Z FGFR 3
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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
