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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
4 Results for "
endosomal acidification
" in MedChemExpress (MCE) Product Catalog:
Products (4)
4 Results for "endosomal acidification" in MCE Product Catalog:
Cat. No.: HY-P10975
CAS No.: 2484874-12-4
Target:
Research Areas:
Cat. No.: HY-W1130452
CAS No.: 2639634-86-7
Lipid C16-C is an ionizable cationic lipid that can be used to prepare lipid nanoparticles (LNPs) for mRNA delivery. Lipid C16-C mediates ApoE-independent macropinocytosis-based mRNA delivery to macrophages, with endosomal acidification enabling endosomal escape and release of mRNA cargo into the cytosol .
Cat. No.: HY-D3122
Target:
Research Areas:
Mem-RhoNox is a fluorescent probe used to detect labile Fe (II) on the plasma membrane surface and inside endosomes during iron uptake in live cells. Mem-RhoNox can anchor to the extracellular surface of the plasma membrane; upon contact with Fe (II), its N-oxide group undergoes a deoxygenation reaction, converting weakly fluorescent Mem-RhoNox into strongly fluorescent Mem-Rhodamine. During transferrin-mediated endocytosis, Mem-RhoNox enters endosomes together with the transferrin-transferrin receptor complex, and reacts with Fe (II) released by transferrin to enable detection of endosomal Fe (II) .
Cat. No.: HY-P11784
CAS No.: 1423724-82-6
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
