5 Results for "

fibrocytes

" in MedChemExpress (MCE) Product Catalog:
Products (5)

5 Results for "fibrocytes" in MCE Product Catalog:

92
92 Cited Publications
Cat. No.: HY-B0673
CAS No.: 53179-13-8
Synonyms: AMR69
Target:  

TGF-beta/Smad CCR

Research Areas:  

Inflammation/Immunology Cancer

Pirfenidone (AMR69) is an antifibrotic agent that attenuates CCL2 and CCL12 production in fibrocyte cells. Pirfenidone has growth-inhibitory effect and reduces TGF-β2 protein levels in human glioma cell lines. Pirfenidone also has anti-inflammatory activities .
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1
1 Cited Publications
Cat. No.: HY-P99165
CAS No.: 1036734-93-6

Target:  

IGF-1R TSH Receptor

Research Areas:  

Endocrinology

Teprotumumab is an IGF-1 receptor (IGF-1R) blocking human monoclonal antibody. Teprotumumab binds to the ligand binding extracellular α-subunit domain of IGF-1R. Teprotumumab inhibits TSH and IGF-1 action in fibrocytes. Teprotumumab attenuates TSH-dependent IL-6 and IL-8 expression and Akt phosphorylation. Teprotumumab can be used for thyroid-associated ophthalmopathy research .
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Cat. No.: HY-B0673R
CAS No.: 53179-13-8
Synonyms: AMR69 (Standard)
Pirfenidone (Standard) is the analytical standard of Pirfenidone. This product is intended for research and analytical applications. Pirfenidone (AMR69) is an antifibrotic agent that attenuates CCL2 and CCL12 production in fibrocyte cells. Pirfenidone has growth-inhibitory effect and reduces TGF-β2 protein levels in human glioma cell lines. Pirfenidone also has anti-inflammatory activities .
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Cat. No.: HY-B0673S1
CAS No.: 1093951-85-9
Synonyms: LYT-100; AMR69-d3
Deupirfenidone-d3 is the deuterium labeled Pirfenidone (HY-B0673). Pirfenidone (AMR69) is an antifibrotic agent that attenuates CCL2 and CCL12 production in fibrocyte cells. Pirfenidone has growth-inhibitory effect and reduces TGF-β2 protein levels in human glioma cell lines. Pirfenidone also has anti-inflammatory activities .
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Cat. No.: HY-B0673S
CAS No.: 1020719-62-3
Synonyms: AMR69-d5
Pirfenidone-d5 (AMR69-d5) is a deuterium labeled Pirfenidone. Pirfenidone is an antifibrotic agent that attenuates CCL2 and CCL12 production in fibrocyte cells. Pirfenidone has growth-inhibitory effect and reduces TGF-β2 protein levels in human glioma cell lines. Pirfenidone also has anti-inflammatory activities .
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