3 Results for "

foretinib

" in MedChemExpress (MCE) Product Catalog:
Products (3)

3 Results for "foretinib" in MCE Product Catalog:

17
17 Cited Publications
Cat. No.: HY-10338
CAS No.: 849217-64-7
Purity:  99.45%
Synonyms: XL880; GSK1363089; GSK089; EXEL-2880
Target:  

VEGFR c-Met/HGFR

Research Areas:  

Cancer

Foretinib is a multi-target tyrosine kinase inhibitor with IC50s of 0.4 nM and 0.9 nM for Met and KDR.
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Cat. No.: HY-10338A
CAS No.: 1226999-07-0
Target:  

c-Met/HGFR VEGFR

Research Areas:  

Cancer

Foretinib phosphate is an orally bioavailable small molecule with potential anti-tumor activity. Foretinib phosphate can selectively inhibit hepatocyte growth factor (HGF) receptor c-MET and vascular endothelial growth factor receptor 2 (VEGFR2), thereby potentially inhibiting tumor angiogenesis, tumor cell proliferation and metastasis. Foretinib phosphate shows different anti-cancer activity from cabozantinib in lung cancer cells and has stronger inhibitory effects on targets such as MEK1/2, FER and AURKB .
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Cat. No.: HY-10338R
CAS No.: 849217-64-7
Synonyms: XL880 (Standard); GSK1363089 (Standard); GSK089 (Standard); EXEL-2880 (Standard)
Research Areas:  

Cancer

Foretinib (Standard) is the analytical standard of Foretinib. This product is intended for research and analytical applications. Foretinib is a multi-target tyrosine kinase inhibitor with IC50s of 0.4 nM and 0.9 nM for Met and KDR.
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