1 Result for "

gerbil stroke model

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "gerbil stroke model" in MCE Product Catalog:

Cat. No.: HY-19210
CAS No.: 157659-79-5
Target:  

Endothelin Receptor

Research Areas:  

Cardiovascular Disease

SB-209670 is an extremely potent and highly specific non-peptide, subnanomolar endothelin (ET) receptor antagonist. SB 209670 selectively inhibits binding of 125I-labeled ET-1 to cloned human ET receptor subtypes ETA and ETB (Ki=0.2 and 18 nM, respectively). SB 209670 produces a dose-dependent reduction in blood pressure in hypertensive rats, protects from ischemia-induced neuronal degeneration in a gerbil stroke model, and attenuates neointima formation following rat carotid artery balloon angioplasty .
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