2 Results for "

gram-negative shock

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "gram-negative shock" in MCE Product Catalog:

  • Targets Recommended:
1
SMAP-29
SMAP-29
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1 Cited Publications
Cat. No.: HY-P2460
CAS No.: 172485-26-6
Target:  

Bacterial Fungal Interleukin Related TNF Receptor

Research Areas:  

Infection Inflammation/Immunology

SMAP‑29 is a cathelicidin antimicrobial peptide with LPS‑binding and anti‑inflammatory properties. SMAP‑29 exerts broad‑spectrum antimicrobial activity against bacteria, fungi and multidrug‑resistant isolates. SMAP‑29 kills pathogens by permeabilizing bacterial membranes, inducing depolarization and cell lysis, and also inhibits inflammatory cytokines while reducing lethality in septic shock and pneumonia models. SMAP-29 can be used for research on bacterial infections, drug-resistant infections, septic shock .
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UDP-3-O-acyl-GlcNAc Tris
UDP-3-O-acyl-GlcNAc Tris
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Cat. No.: HY-W585865
CAS No.: 112710-84-6
Synonyms: UDP-3-O-(3-hydroxytetradecanoyl)-N-acetylglucosamine Tris
Category:  

Infection Natural Products Endogenous metabolite Disease Research Fields

Target:  

Endogenous Metabolite Bacterial

UDP-3-O-acyl-GlcNAc Tris (UDP-3-O-(3-hydroxytetradecanoyl)-N-acetylglucosamine Tris) serves as a deacetylation substrate and biosynthetic intermediate in the biosynthetic pathways of lipid A and Kdo2-lipid A in Escherichia coli. UDP-3-O-acyl-GlcNAc Tris undergoes enzymatic deacetylation via LpxC to produce UDP-3-O-[(R)-3-hydroxymyristoyl]glucosamine and release acetate. UDP-3-O-acyl-GlcNAc Tris accumulates in Escherichia coli extracts in the absence of [(R)-3-hydroxymyristoyl]-acyl carrier protein. UDP-3-O-acyl-GlcNAc Tris can be used in studies related to Gram-negative shock .
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