1 Result for "

hX2

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "hX2" in MCE Product Catalog:

Cat. No.: HY-183050
CAS No.: 3036387-75-1
Research Areas:  

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HEP-50768 is an orally active and selective MRGPRX4 (hX4) antagonist. HEP-50768 suppresses basal and bile-acid-stimulated hX4 activity. HEP-50768 binds the receptor’s transmembrane pocket and induces extracellular loop rearrangements. HEP-50768 modulates GPCR microswitch motifs and reduces bile-acid-induced pruritic scratching behaviors. HEP-50768 can be used for the research of cholestatic pruritus .
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