5 Results for "

human ADAM17

" in MedChemExpress (MCE) Product Catalog:
Products (5)

5 Results for "human ADAM17" in MCE Product Catalog:

Cat. No.: HY-RS00271
Domaines de recherche:  

Others

ADAM17 Human Pre-designed siRNA Set A contains three designed siRNAs for ADAM17 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-P992406

Target:  

MMP IFNAR

Domaines de recherche:  

Cancer

MEDI-3622 is a human monoclonal antibody against ADAM17. MEDI-3622 blocks the ADAM17-mediated shedding of CD16A and CD62L on NK cells, and binds with high specificity to a surface loop unique to the metalloprotease catalytic domain of ADAM17. MEDI-3622 enhances IFNγ production by NK cells when they bind to antibody-coated tumor cells. MEDI-3622 can be used in the research of ovarian cancer, Burkitt lymphoma, head and neck cancer, and colorectal cancer .
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Cat. No.: HY-P992185

Target:  

MMP

Domaines de recherche:  

Inflammation/Immunology

Anti-ADAM17 Antibody is a monoclonal antibody targeting ADAM17. It can be used in ELISA, FACS, and functional assays. For isotype controls of Anti-ADAM17 Antibody, please refer to Human IgG1 kappa, Isotype Control (HY-P99001).
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Cat. No.: HY-137839
CAS No.: 927827-98-3
Target:  

MMP

Domaines de recherche:  

Inflammation/Immunology

Anti-inflammatory agent 121 is a protease inhibitor, with IC50 values against different targets as follows: 1.3 μM (Staphylococcus aureus type I staphylokinase), 2.2 μM (Staphylococcus aureus type II staphylokinase), 2.3 μM (human MMP-1), 2.7 μM (human MMP-2), 1.4 μM (human MMP-8), 4.6 μM (human MMP-9), and 79 μM (human ADAM17). Anti-inflammatory agent 121 inhibits the activities of staphylococcal serine protease glutamyl endopeptidase (V8 protease) and cysteine protease staphylococcal protease B in Staphylococcus aureus cultures. Anti-inflammatory agent 121 inhibits protease activity in skin wash samples, metalloprotease (staphylokinase) activity in Staphylococcus aureus culture supernatants, and staphylokinase-mediated activation of pro-urokinase-type plasminogen activator (pro-uPA). Anti-inflammatory agent 121 can be used in the research of atopic dermatitis .
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Cat. No.: HY-P702499
Pureté:  ≥ 80%, as determined by reducing SDS-PAGE.
Synonyms: ADAM 17; ADAM metallopeptidase domain 17; ADAM metallopeptidase domain 18; ADAM17; ADAM18; CD156b antigen; CD156b; CSVP; disintegrin and metalloproteinase domain-containing protein 17; EC 3.4.24.86; MGC71942; Snake venom-like protease; TACE; TACEcSVP; TNF-alpha convertase; TNF-alpha converting enzyme; TNF-alpha-converting enzyme; tumor necrosis factor, alpha, converting enzyme
Species:  
Source:  
CHO
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