2 Results for "

human Nav1.1-1.2

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "human Nav1.1-1.2" in MCE Product Catalog:

Cat. No.: HY-122001
CAS No.: 1235406-03-7
Purity:  99.69%
Target:  

Sodium Channel

Research Areas:  

Neurological Disease

PF-05186462 is a potent and selective inhibitor of human Nav1.7 voltage-dependent sodium channel, with an IC50 of 21 nM. PF-05186462 shows significant selectivity for Nav1.7 versus other sodium channels (Nav 1.1, 1.2, 1.3, 1.4, 1.5, 1.6, and 1.8). PF-05186462 can be used for the research of acute or chronic pain .
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Cat. No.: HY-P5152
Target:  

Sodium Channel

Research Areas:  

Neurological Disease

Scorpion toxin Tf2 is a selective human voltage-gated sodium channel Nav1.3 (hNav1.3) activator. Scorpion toxin Tf2 selectively shifts the channel's activation voltage to more negative values, enabling channel opening at resting membrane potentials. Scorpion toxin Tf2 can be used for the research of epilepsy, nociception (after spinal cord injury) .
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