1 Result for "

lestaurtinib

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "lestaurtinib" in MCE Product Catalog:

4
4 Cited Publications
Cat. No.: HY-50867
CAS No.: 111358-88-4
Synonyms: CEP-701; KT-5555
Research Areas:  

Cancer

Lestaurtinib (CEP-701) is an orally active and selective RPTKs (receptor protein tyrosine kinase) inhibitor, competitively inhibits ATP binding to the TrkA/B/C domain. Lestaurtinib inhibits RPTKs phosphorylation, with IC50s of 2, 25 and 0.9 nM for FLT3, TrkA and JAK2, respectively. Lestaurtinib induces apoptosis and cycle arrest, also can inhibit growth of tumor .
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