1 Result for "

mG2N001

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "mG2N001" in MCE Product Catalog:

Cat. No.: HY-157998
CAS No.: 2760515-88-4
Target:  

mGluR Src

Research Areas:  

Others

mG2N001 is a negative allosteric modulator (NAM) (IC50: 93 nM) of the metabotropic glutamate receptor mGluR2 and binds to mGluR2 as an antagonist (Ki: 63 nM). mG2N001 is microparticle- and plasma-stable, and its radioisotope [11C]mG2N001 can be used in PET imaging. [11C]mG2N001 has good brain heterogeneity and brain penetration, and can selectively accumulate in mGluR2-rich regions, producing high-contrast brain images .
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