7 Results for "

mertansin

" in MedChemExpress (MCE) Product Catalog:
Products (7)

7 Results for "mertansin" in MCE Product Catalog:

28
28 Cited Publications
Cat. No.: HY-19792
CAS No.: 139504-50-0
Synonyms: DM1; Maytansinoid DM1
Research Areas:  

Cancer

Mertansine (DM1) is a microtubulin inhibitor and is an antibody-conjugatable maytansinoid that is developed to overcome systemic toxicity associated with maytansine and to enhance tumor-specific delivery. Mertansine can be attached to a monoclonal antibody with a linker to create an antibody-drug conjugate (ADC) .
loading...
    loading...
Cat. No.: HY-132262
CAS No.: 1008106-64-6
Synonyms: IMGN-901; BB-1090
Research Areas:  

Cancer

Lorvotuzumab mertansine is an ADC consisting of a humanized N901 monoclonal antibody against CD56 bound to maytansinoid DM1 via a stable disulfide linker. Lorvotuzumab mertansine has antitumor activity .
loading...
    loading...
Cat. No.: HY-P99492
CAS No.: 400010-39-1
Synonyms: SB-408075; huC242-DM1
Cantuzumab mertansine (SB-408075; huC242-DM1), an ADC, is an immunoconjugate of the potent maytansine derivative (DM1 (HY-19792)) and the humanized monoclonal antibody (huC242) directed to CanAg. Cantuzumab mertansine has cytotoxic toward colon cancer cells and has broad antitumor efficacy against a range of CanAg-positive human tumor xenografts .
loading...
    loading...
Cat. No.: HY-W757436
(R)-Mertansine- 13C,d3 is the deuterium labeled and 13C-labeled (R)-Mertansine.
loading...
    loading...
Cat. No.: HY-19792S2
Synonyms: DM1-d3; Maytansinoid DM1-d3
Mertansine-d3 (DM1-d3) is the deuterium labeled Mertansine (HY-19792). Mertansine (DM1) is a microtubulin inhibitor and is an antibody-conjugatable maytansinoid that is developed to overcome systemic toxicity associated with maytansine and to enhance tumor-specific delivery. Mertansine can be attached to a monoclonal antibody with a linker to create an antibody-drug conjugate (ADC) .
loading...
    loading...
Cat. No.: HY-19792S
Synonyms: DM1-13C,d3; Maytansinoid DM1-13C,d3
Mertansine- 13C,d3 (DM1- 13C,d3) is the 13C- and deuterium labeled Mertansine (HY-19792). Mertansine (DM1) is a microtubulin inhibitor and is an antibody-conjugatable maytansinoid that is developed to overcome systemic toxicity associated with maytansine and to enhance tumor-specific delivery. Mertansine can be attached to a monoclonal antibody with a linker to create an antibody-drug conjugate (ADC) .
loading...
    loading...
Cat. No.: HY-P81055
Synonyms: mertansine, Maytansinoid DM1, DM 1, 139504-50-0

Host:  

Mouse

Application:  

ELISA

Reactivity:  

Species independent

loading...
    loading...