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Results for "

mouse EBP

" in MedChemExpress (MCE) Product Catalog:

7

Inhibitors & Agonists

2

Peptides

2

Antibodies

3

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-162351
    EBP-IN-1

    		Emopamil Binding Protein Metabolic Disease
    EBP-IN-1 is an orally active, blood-brain barrier-permeable inhibitor of emopamil binding protein (EBP). EBP-IN-1 has an IC50 of 8.2 μM against human ERG potassium channels (in CHO background). By inhibiting the sterol isomerase activity of EBP, EBP-IN-1 causes the accumulation of Zymostenol (HY-113345), and exhibits strong target binding in the brain after repeated administration in rodents. EBP-IN-1 also promotes oligodendrocyte formation in human cortical organoids and can be used in research related to multiple sclerosis .
    EBP-IN-1
  • HY-P10323
    T7 Peptide

    Tumstatin (74-98), human

    		 Integrin FAK mTOR Apoptosis Cancer
    T7 Peptide is a protein synthesis inhibitor and anti-angiogenic agent, with a Kd of 10 nM for human transferrin receptor. T7 Peptide inhibits the phosphorylation of focal adhesion kinase, the activation of phosphatidylinositol 3-kinase and Akt, the kinase activity of mTOR, as well as the phosphorylation of 4E-BP1 in endothelial cells. T7 Peptide induces G0/G1 cell cycle arrest, apoptosis and protective autophagy in hepatocellular carcinoma cells, and suppresses tumor growth in mouse models. T7 Peptide is applicable to research related to cancer, glioblastoma, hepatocellular carcinoma and glioma .
    T7 Peptide
  • HY-P10323A
    T7 Peptide TFA

    Tumstatin (74-98), human TFA

    		 Integrin FAK mTOR Apoptosis Cancer
    T7 Peptide TFA is a protein synthesis inhibitor and anti-angiogenic agent, with a Kd of 10 nM for human transferrin receptor. T7 Peptide TFA inhibits the phosphorylation of focal adhesion kinase, the activation of phosphatidylinositol 3-kinase and Akt, the kinase activity of mTOR, as well as the phosphorylation of 4E-BP1 in endothelial cells. T7 Peptide TFA induces G0/G1 cell cycle arrest, apoptosis and protective autophagy in hepatocellular carcinoma cells, and suppresses tumor growth in mouse models. T7 Peptide TFA is applicable to research related to cancer, glioblastoma, hepatocellular carcinoma and glioma .
    T7 Peptide TFA
  • HY-RS18892
    Ebp Mouse Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    Ebp Mouse Pre-designed siRNA Set A contains three designed siRNAs for Ebp gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

    Ebp Mouse Pre-designed siRNA Set A
    Ebp Mouse Pre-designed siRNA Set A
  • HY-RS20664
    Eif4ebp2 Mouse Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    Eif4ebp2 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Eif4ebp2 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

    Eif4ebp2 Mouse Pre-designed siRNA Set A
    Eif4ebp2 Mouse Pre-designed siRNA Set A
  • HY-RS20227
    Eif4ebp1 Mouse Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    Eif4ebp1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Eif4ebp1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

    Eif4ebp1 Mouse Pre-designed siRNA Set A
    Eif4ebp1 Mouse Pre-designed siRNA Set A
  • HY-181650
    T133

    		mTOR Akt Ribosomal S6 Kinase (RSK) Apoptosis Autophagy PI3K Cancer
    T133 is an orally active ATP-competitive mTOR inhibitor with an IC50 of 0.34 nM and a Ki of 0.17 nM. T133 suppresses phosphorylation of AKT, S6K1, and 4EBP1. T133 inhibits cancer cell proliferation and migration, induces apoptosis, cell cycle arrest, and autophagy. T133 exhibits dose-dependent antitumor efficacy in xenograft mouse models. T133 can be used for the research of cancer, such as gastric cancer and lung cancer .
    T133

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