4 Results for "

myocardin

" in MedChemExpress (MCE) Product Catalog:
Products (4)

4 Results for "myocardin" in MCE Product Catalog:

2
2 Cited Publications
Cat. No.: HY-120855
CAS No.: 1207113-88-9
Purity:  99.29%
Target:  

Ras

Research Areas:  

Cardiovascular Disease

CCG-100602 is a specific inhibitor of myocardin-related transcription factor A/serum response factor (MRTF-A/SRF) signaling. CCG-100602 specifically block MRTF-A nuclear localization and thus inhibit the fibrogenic transcription factor SRF .
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1
1 Cited Publications
Cat. No.: HY-121750
CAS No.: 1922098-69-8
Purity:  99.53%
Target:  

Ras ROCK

Research Areas:  

Cancer

CCG-222740 is an orally active and selective Rho/myocardin-related transcription factor (MRTF) pathway inhibitor . CCG-222740 is also a potent inhibitor of alpha-smooth muscle actin protein expression. CCG-222740 effectively reduces fibrosis in skin and blocks melanoma metastasis .
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Cat. No.: HY-153078
CAS No.: 1922098-90-5
Purity:  99.68%
Target:  

Ras

Research Areas:  

Cancer

MRTF/SRF-IN-1 (example 41) is an inhibitor of both myocardin-related transcription factor and serum response factor (MRTF/SRF). MRTF/SRF-IN-1 can be used for research for preventing cancer and fibrosis .
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Cat. No.: HY-132187
CAS No.: 1670-26-4
Purity:  99.50%
Sphingosylphosphorylcholine is a bioactive lipid and a major component of plasma high-density lipoprotein that binds to OGR1 with a Kd of 33.3 nM. Sphingosylphosphorylcholine triggers delayed phosphorylation of Smad2, upregulates α-SMA expression, and activates TRPM3. Sphingosylphosphorylcholine reduces Apoptosis and upregulates the expression of uPA and its receptor uPA-R. Sphingosylphosphorylcholine exerts anti-apoptotic, anti-cardiac hypertrophy and pro-wound healing effects. Sphingosylphosphorylcholine induces scratching behavior in mice. Sphingosylphosphorylcholine is used in studies related to atopic dermatitis, promyelocytic leukemia, heart failure, myocardial ischemia/reperfusion injury, ovarian cancer, breast cancer, pancreatic cancer, and skin wound healing disorders in genetically impaired healing diabetes .
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