1 Result for "

pangenotype

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "pangenotype" in MCE Product Catalog:

Cat. No.: HY-125182
CAS No.: 2649904-85-6
Target:  

Cyclophilin HCV

Research Areas:  

Infection

SMCypI C31 is a non-peptidic cyclophilin inhibitor with potent peptidyl-prolyl cis/trans isomerases (PPIase) inhibitory activity (IC50 of 0.1 µM). SMCypI C31 shows pangenotype anti-HCV activity with EC50s ranging from 1.20 to 7.76 μM for genotype 1a, 1b, 2a, 3a, and 5a HCV subgenomic replicons (HCV-SGRs) and chimeric genotype 2a/4a HCV-SGRs. SMCypI C31 disrupts the cyclophilin A-NS5A interaction .
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